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AF488-labeled Human FAP CAR Detection Reagent, His Tag (XS-1223-LX21)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Specifications

  • Target
  • FAP
  • Organism
  • Human
  • Application
  • Used for evaluating CAR expression.
  • Purity
  • >90%
  • Endotoxin Level
  • Less than 1.0 EU per μg by the LAL method.
  • Storage
  • For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    Please protect from light and avoid repeated freeze-thaw cycles.
  • Shelf-Life
  • Stable as supplied until expiry date on label.
  • Application Notes
  • This product is recommended for FC application, and the optimal working dilutions should be determined by the end user.
  • Diseases
  • Lung malignancy
  • Molecular Characterization
  • The CAR detection reagent contains AA Leu 26 - Asp 760 of Human FAP.
  • Conjugation
  • AF488
  • Size
  • 25µg; 100µg
  • Formulation
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
  • Expression
  • Human HEK293 cells
  • Host Species
  • Human
  • Species Reactivity
  • Human
  • Form
  • Lyophilized

Target

  • Target Introduction
  • The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelialmesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Target Alternative Names
  • fibroblast activation protein alpha
  • Entrez Gene ID
  • 2191

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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