anti-EBV TCR, pMP71(TCR-L016)

The vector of anti-EBV T cell receptor (TCR) is constructed for the engineering of T cell to target EBV. The T cells are genetically modified through transduction with a retroviral vector expressing EBV-specific T cell receptor. And the vector product was designed for the treatment of infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma,gastric cancer,nasopharyngeal carcinoma, multiple sclerosis, and lymphomatoid granulomatosis.


Details


Target
EBV
Target Species
EBV
Epitope
AVFDRKSDAK
Format
Cysteine-modified TCR
HLA
HLA- A11
Targeting Diseases
Infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma,gastric cancer,nasopharyngeal carcinoma, multiple sclerosis, and lymphomatoid granulomatosis.
Vector Name
pMP71
Vector Length
3817bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
EBNA3A nuclear protein
Official Symbol
LMP2
Synonyms
LMP2; EBNA3A nuclear protein; EBNA3A; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; EBV infection
Introduction
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family,
and is one of the most common viruses in humans.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CarcinomaLymphomaViral Infection

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Fax: 1-631-207-8356
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