anti-HA-1 TCR, pMP71(TCR-L039)

The vector of anti-HA-1 T cell receptor (TCR) is constructed for the engineering of T cell to target HA-1. The T cells are genetically modified through transduction with a retroviral vector expressing HA-1-specific T cell receptor. And the vector product was designed for the treatment of hematological malignancies.


Details


Target
HA-1
Epitope
VLHDDLLEA
Format
Codon optimized and cysteine modified TCR
HLA
HLA-A2
Targeting Diseases
hematological malignancies
Vector Name
pMP71
Vector Length
3817bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
histocompatibility (minor) HA-1
Official Symbol
HMHA1
Gene ID
UniProt ID
Synonyms
HA-1; HLA-HA1; ARHGAP45; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; hematological malignancies
Introduction
HMHA1 (Histocompatibility (Minor) HA-1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Rho GTPase cycle. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP19.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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