anti-HBV TCR, pMP71(TCR-L043)

The vector of anti-HBV T cell receptor (TCR) is constructed for the engineering of T cell to target HBV. The T cells are genetically modified through transduction with a retroviral vector expressing HBV-specific T cell receptor. And the vector product was designed for the treatment of Hepatitis B encoding at least one virus (HBV) and hepatocellular carcinoma (HCC) .


Details


Target
HBV
Target Species
HBV
Epitope
SIVSPFIPLL
Format
Cysteine-modified TCR
HLA
HLA-A0201
Targeting Diseases
Hepatitis B encoding at least one virus (HBV) and hepatocellular carcinoma (HCC)
Vector Name
pMP71
Vector Length
3817bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
Hepatitis B virus
Official Symbol
HBV
Synonyms
HbsAg; HBV; Major surface antigen; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Hepatitis B encoding at least one virus; HBV; hepatocellular carcinoma; HCC
Introduction
epatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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