Close

Anti-KIR3DS1 h(KIR3DS1-DAP12) KIR-CAR, pCDCAR1 (XS-0622-ZP3517)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Although the classical second-generation CAR design has been shown to be very effective when used to treat hematological malignancies, this traditional CAR design has failed to promote equally significant antitumor activity in non-hematological cancers. Killer immunoglobulin-like receptors (KIRs) are an important family of immune receptors used by T cells and NK cells. Considering that their multi-chain design may have the advantage of evolutionary selection, Creative Biolabs designed a more realistic CAR design based on unique KIRs found in humans and non-human primates. This KIR-based CAR (KIR-CAR) naturally interacts with the DAP12 protein, delivering important signals to T cells that promote T cell proliferation, cytokine secretion, and cytotoxicity.

Specific Inquiry

  • Size:
  • Marker:
  • Form:
  Add to Cart

Details

  • Target
  • KIR3DS1
  • Targeting Cell Type
  • T Cell/NK Cell
  • Generation
  • Second
  • Vector Name
  • pCDCAR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral vector
  • Receptor Construction
  • KIR3DS1-Transmembrane & Cytoplasmic Domain-DAP12

Customize Your CAR Products

Cannot find the desired product? Don't worry, just try our online CAR and CAR cell customizing system, which offers full options to meet all unique needs, including but not limited to conventional or unconventional CAR constructs, as well as a variety of vectors and cells. The customization process can be completed with just a few simple clicks, please feel free to try it out.
CAR and CAR Cell Customizing System

Customer Reviews and Q&As

There are currently no customer reviews or questions for Anti-KIR3DS1 h(KIR3DS1-DAP12) KIR-CAR, pCDCAR1 (XS-0622-ZP3517). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Online Inquiry

For any technical issues or product/service related questions, please leave your information below. Our team will contact you soon.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Key Updates
Newsletter NEWSLETTER

The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders

LEARN MORE NEWSLETTER
New Solution NEW SOLUTION

CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.

LEARN MORE SOLUTION
NOVEL SOLUTION NOVEL TECHNOLOGY

Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.

LEARN MORE NOVEL TECHNOLOGY
NEW TECHNOLOGY NEW SOLUTION

Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.

LEARN MORE SOLUTION
Receive our latest news and insights.