All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Although the classical second-generation CAR design has been shown to be very effective when used to treat hematological malignancies, this traditional CAR design has failed to promote equally significant antitumor activity in non-hematological cancers. Killer immunoglobulin-like receptors (KIRs) are an important family of immune receptors used by T cells and NK cells. Considering that their multi-chain design may have the advantage of evolutionary selection, Creative Biolabs designed a more realistic CAR design based on unique KIRs found in humans and non-human primates. This KIR-based CAR (KIR-CAR) naturally interacts with the DAP12 protein, delivering important signals to T cells that promote T cell proliferation, cytokine secretion, and cytotoxicity.
There are currently no customer reviews or questions for Anti-KIR3DS1 h(KIR3DS1-DAP12) KIR-CAR, pCDCAR1 (XS-0622-ZP3517). Click the button below to contact us or submit your feedback about this product.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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