anti-MAGEA12 TCR, pMSGV1(TCR-L059)

The vector of anti-MAGEA12 T cell receptor (TCR) is constructed for the engineering of T cell to target Human MAGEA12. The T cells are genetically modified through transduction with a retroviral vector expressing MAGEA12-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.


Details


Target
MAGEA12
Target Species
Human
Epitope
VRIGHLYIL
Format
Non-modified TCR
HLA
HLA-Cw7
Targeting Diseases
Melanoma
Vector Name
pMSGV1
Vector Length
6700-8070bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
MAGE family member A12
Official Symbol
MAGEA12
Gene ID
UniProt ID
Synonyms
CT1.12; MAGE12; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Melanoma
Introduction
This gene is closely related to several other genes clustered on chromosome X. These genes may be overexpressed in tumors. Multiple alternatively spliced variants encoding the same protein have been identified.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Carcinoma

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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