Anti-MAP2K1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-3723-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-MAP2K1 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
MAP2K1

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
5604

UniProt ID
Q02750

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-3723-FY	25/MEK1	Mouse	Human	IgG2a	Human MEK1 Recombinant Protein
DMAb-3724-FY	CBFYM-0006	Human	Human	IgG1
DMAb-3725-FY	CBFYM-0053	Mouse	Human	IgG1, k	Synthetic peptide corresponding to amino acid residues near the C-terminus conjugated to KLH
DMAb-3726-FY	CBFYM-0185	Mouse	Human	IgG2a
DMAb-3727-FY	CBFYM-0269	Rabbit	Human	IgG
DMAb-3728-FY	CBFYM-0333	Mouse	Human	IgG1, k	Phosphorylated Human MEK1 Peptide
DMAb-3729-FY	CBFYM-0552	Rabbit	Human	IgG
DMAb-3730-FY	CBFYM-0553	Mouse	Mouse	IgG1
DMAb-3731-FY	CBFYM-1414	Mouse	Human	IgG2a	Synthetic peptide corresponding to a portion of MKK1/2 (MAP kinase kinase 1/2)
DMAb-3732-FY	CBFYM-1415	Mouse	Human	IgG1, k	MEK1 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His-MEK1)
DMAb-3733-FY	CBFYM-1416	Mouse	Human	IgG2b	Protein expressed in 293T cell transfected with human MAP2K1 expression vector
DMAb-3734-FY	CBFYM-1417	Mouse	Human		Mitogen Activated Protein Kinase Kinase 1
DMAb-3735-FY	CBFYM-1418	Human	Human		Full length recombinant human MEK 1 expressed in Sf9 cells
DMAb-3736-FY	CBFYM-1419	Mouse	Human	IgG1	Native MEK and recombinant MEK1
DMAb-3737-FY	CBFYM-1420	Mouse	Human	IgG1, k	Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: GRPLSSYGMD SRPPMAIFEL LDYIVNEPPP KLPSGVFSLE FQDFVNKCLI KNPAERADLK QLMVHAFIKR SDAEEVDFAG WLCSTIGLNQ PSTPTHAAGV
DMAb-3738-FY	CBFYM-1421	Rabbit	Human	IgG
DMAb-3739-FY	CBFYM-1422	Mouse	Human	IgG1	Full length human recombinant protein of human MAP2K1(NP_002746) produced in HEK293T cell
DMAb-3740-FY	CBFYM-1423	Mouse	Human	IgG2a	Full length human recombinant protein of human MAP2K1(NP_002746) produced in HEK293T cell
DMAb-3741-FY	CBFYM-1424	Rabbit	Human	IgG	Synthetic peptide (KLH coupled) corresponding to human MEK1
DMAb-3742-FY	CBFYM-1425	Mouse	Human	IgG	Protein expressed in 293T cell transfected with human MAP2K1 expression vector
DMAb-3743-FY	CBFYM-1426	Mouse	Human	IgG2a	Full length MEK1 proteins
DMAb-3744-FY	CBFYM-1427	Mouse	Human	IgG2a	E. coli-derived recombinant human MEK1, Lys2-Val393 (Ser218Asp, Ser222Asp)
DMAb-3745-FY	CBFYM-1428	Mouse	Human	IgG1, k	Recombinant protein between 1-393 amino acids from human MP2K1
DMAb-3746-FY	CBFYM-1429	Rabbit	Human	IgG	Recognizes MEK1
DMAb-3747-FY	CBFYM-1430	Rabbit	Human	IgG	Recombinant peptide corresponding to amino acids surrounding the TEY motif in the activation loop of human phospho-MEK1
DMAb-3748-FY	CBFYM-1431	Mouse	Human	IgG1, k	A mouse immunized with a recombinant protein between 1-393 amino acids from human MP2K1
DMAb-3749-FY	CBFYM-1432	Mouse	Human	IgG2a
DMAb-3750-FY	CBFYM-1433	Mouse	Human	IgG1
DMAb-3751-FY	CBFYM-1434	Rabbit	Human
DMAb-3752-FY	CBFYM-1435	Mouse	Human	IgG2a	Recombinant Xenopus MEK1
DMAb-3753-FY	CBFYM-1436	Mouse	Human	IgG1
DMAb-3754-FY	CBFYM-1437	Mouse	Human

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-MAP2K1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-3723-FY)

Specifications

Target

Customer Reviews and Q&As

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