anti-Tax TCR, pMP71(TCR-L109)

The vector of anti-Tax T cell receptor (TCR) is constructed for the engineering of T cell to target Human T cell lymphotrophic virus Tax. The T cells are genetically modified through transduction with a retroviral vector expressing Tax-specific T cell receptor. And the vector product was designed for the treatment of Adult T cell leukaemia (ATL).


Details


Target
Tax
Target Species
HTLV-1
Epitope
LLFGYPVYV
Format
Single-chain TCR
Targeting Diseases
Adult T cell leukaemia (ATL)
Vector Name
pMP71
Vector Length
3817bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
Tax
Official Symbol
tax
Gene ID
UniProt ID
Synonyms
TP2; TRT; CMM9; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Cancer
Introduction
The Tax protein of HTLV1 is an autoregulator of enhanced viral RNA transcription and it trans activates the viral 21 bp enhancer.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Leukemia

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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