Anti-Cytochrome P450 T cell receptor (JL12), pCDTCR1(TCR-C037Z)

The vector of anti-Cytochrome P450 T cell receptor (TCR) is constructed for the engineering of T cell to target Human Cytochrome P450. The T cells are genetically modified through transduction with a lentiviral vector expressing Cytochrome P450-specific T cell receptor.


Details


Target
Cytochrome P450
Target Species
Human
Epitope
KPIVVLHGY
Format
Non-modified
HLA
HLA-B35
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
JL12
Antibody Host
Human

Target


Gene Name
Cytochrome P450
Official Symbol
Cytochrome P450
Synonyms
Cytochrome P450; CYP
Introduction
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins. CYPs use a variety of small and large molecules as substrates in enzymatic reactions. They are, in general, the terminal oxidase enzymes in electron transfer chains, broadly categorized as P450-containing systems. The term P450 is derived from the spectrophotometric peak at the wavelength of the absorption maximum of the enzyme (450 nm) when it is in the reduced state and complexed with carbon monoxide.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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45-1 Ramsey Road, Shirley, NY 11967, USA
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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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