Human PSCA CAR Detection Reagent, His Tag (Biotinylated) (XS-0423-LX83)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Human PSCA CAR Detection Reagent, His Tag (Biotinylated) is applied for evaluating Human PSCA CAR expression, and is suitable for FC application.

Specific Inquiry

Add to Cart

Specifications

Target
PSCA

Organism
Human

Application
Used for evaluating CAR expression

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
The optimal working dilutions should be determined by the end user.

Diseases
Prostate cancer

Molecular Characterization
The CAR detection reagent contains AA Leu 12 - Ser 86 of Human PSCA.

Conjugation
Biotinylated

Size
25 tests; 100 tests

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
HEK293 cell

Host Species
Human

Species Reactivity
Human

Form
Lyophilized

Target

Target Introduction
This gene encodes a glycosylphosphatidylinositolanchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is upregulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

Target Alternative Names
prostate stem cell antigen

Entrez Gene ID
8000

UniProt ID
P57096-1

Related Resources

Overview of PSCA-Targeted CAR Cell Therapies

Customer Reviews and Q&As

There are currently no customer reviews or questions for Human PSCA CAR Detection Reagent, His Tag (Biotinylated) (XS-0423-LX83). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.