Get a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Focused on the recent advances in CAR structure design and manufacturing, Creative Biolabs is dedicated to improving the prospects for the future development of CAR-T cell therapy. Based on innovative manufacturing technology, we are developing a new Silence™ CAR platform that introduces gene-silencing elements to a CAR construct. To advance your CAR-T cell research, we offer a full range of service custom Silence™ CAR-T development, from Silence™ CAR design to cellular functional validation and expansion.
Fig.1 Silence™ CAR-T.
As pioneers in the next-generation CAR-T development, we provide one-stop Silence™ CAR-T development services, ranging from design, plasmid synthesis and construction, transfection, and expression evaluation to functional testing. Our Silence™ CAR-T platform combines the RNAi technology that silences genes by generating knockdown at the mRNA level. In order to verify the silencing effects as expected, we perform real-time qRT-PCR to test RNA expression level and Western blot to test protein expression level. We will take all testing details into consideration, such as positive/negative controls and the cell transfection efficiency.
Creative Biolabs has developed a variety of CAR-T products to make breakthroughs in cell therapies. We provide you with the overall solution covering the workflow of Silence™ CAR development. Our scientists can design and construct CARs including classical routes of CARs and special CARs. We are committed to being a trusted partner and providing you with the information you need. Once we know the details of your project, we offer scientific support as well as an overall solution to help get you started!
Fig.2 Workflow of Silence™ CAR-T therapy development.
Do not hesitate to contact us for a consultation on your project and study design.
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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