237 epitope

The 237 antibody is a model murine monoclonal scFv, it recognizes a mutated glycopeptide expressed by an aggressive murine fi brosarcoma tumor cell line called Ag104a. The tumor-specifi c glycopeptide is generated as a result of a mutated chaperone protein Cosmc that when repaired, ablates the 237 neo-epitope. Ag104A cells express both the OTS8 transmembrane protein and a mutated Cosmcchaperone, resulting in naturally high levels of expression of the 237 epitope.

Anti-237 epitope CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-MZ103 T cell Second 237 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
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