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ANTXR1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-MV-01LX436 Anti-ANTXR1 (L2) h(41BB-CD3ζ) CAR, pMMLV Human L2 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX437 Anti-ANTXR1 (1D2) h(41BB-CD3ζ) CAR, pMMLV Human 1D2 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX438 Anti-ANTXR1 (T803) h(41BB-CD3ζ) CAR, pMMLV Human T803 Humanized scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX439 Anti-ANTXR1 (M830) h(41BB-CD3ζ) CAR, pMMLV Human M830 Human scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX440 Anti-ANTXR1 (L3) h(41BB-CD3ζ) CAR, pMMLV Human L3 Human scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX441 Anti-ANTXR1 (L1) h(41BB-CD3ζ) CAR, pMMLV Human L1 Human scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-1122-YF2774 Anti-ANTXR1 TCR-ABR (scFv-CD3γ, XW-14) CAR Plasmid, pCDCAR1 Human XW-14 Mouse scFv-CD3γ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2775 Anti-ANTXR1 TCR-ABR (scFv-CD3γ, XW-15) CAR Plasmid, pCDCAR1 Human XW-15 Human scFv-CD3γ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF3694 Anti-ANTXR1 TCR-ABR (scFv-CD3δ, XW-14) CAR Plasmid, pCDCAR1 Human XW-14 Mouse scFv-CD3δ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF3695 Anti-ANTXR1 TCR-ABR (scFv-CD3δ, XW-15) CAR Plasmid, pCDCAR1 Human XW-15 Human scFv-CD3δ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF4614 Anti-ANTXR1 TCR-ABR (scFv-CD3ε, XW-14) CAR Plasmid, pCDCAR1 Human XW-14 Mouse scFv-CD3ε Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF4615 Anti-ANTXR1 TCR-ABR (scFv-CD3ε, XW-15) CAR Plasmid, pCDCAR1 Human XW-15 Human scFv-CD3ε Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF5534 Anti-ANTXR1 (XW-14) h(CD28-CD3ζ) CAR, pAAV Human XW-14 Mouse scFv-CD28-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF5535 Anti-ANTXR1 (XW-15) h(CD28-CD3ζ) CAR, pAAV Human XW-15 Human scFv-CD28-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF6454 Anti-ANTXR1 (XW-14) h(41BB-CD3ζ) CAR, pAAV Human XW-14 Mouse scFv-41BB-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF6455 Anti-ANTXR1 (XW-15) h(41BB-CD3ζ) CAR, pAAV Human XW-15 Human scFv-41BB-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF7374 Anti-ANTXR1 (XW-14) h(CD28-41BB-CD3ζ) CAR, pAAV Human XW-14 Mouse scFv-CD28-41BB-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF7375 Anti-ANTXR1 (XW-15) h(CD28-41BB-CD3ζ) CAR, pAAV Human XW-15 Human scFv-CD28-41BB-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-0323-LX3986 TRAC-ANTXR1 (X3XT188) h(CD28-41BB-CD3ζ) replaced CAR, pcDNA Vector Human X3XT188 Mouse Homology arm-EF1a-scFv-CD28-41BB-CD3ζ-Homology arm Nonviral T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX4475 TRAC-ANTXR1 (X3XT193) h(ICOS-4-1BB-CD3ζ) replaced CAR, pcDNA Vector Human X3XT193 Human Homology arm-EF1a-scFv-ICOS-41BB-CD3ζ-Homology arm Nonviral T cell CAR-T   Add to Cart   Datasheet
XS-0823-LX1 Anti-hANTXR1 (L2) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human L2 Adenoviral vectors   Add to Cart   Datasheet
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