CMV pp65

Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens.

Associated Disease
  • HCMV infection
Anti-CMV pp65 TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-L138 CMV TCRCD8-CMV#1 Human ~8kb Lentiviral PLKMLNIPSINVHHYPSAAERKH Non-modified HLA-B3501 Inquiry
TCR-L139 CMV TCRCD8-CMV#4 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L140 CMV TCRCD8-CMV#8 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L141 CMV TCRCD8-CMV#9 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L142 CMV TCRCD8-CMV#10 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L143 CMV TCRCD8-CMV#11 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L144 CMV TCRCD8-CMV#12 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L145 CMV TCRCD8-CMV#14 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L146 CMV TCRCD8-CMV#15 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L147 CMV TCRCD8-CMV#16 Human ~8kb Lentiviral NLVPMVATV Non-modified HLA-A0201 Inquiry
TCR-L148 CMV TCRCD4-CMV#1 Human ~8kb Lentiviral PLKMLNIPSINVHHYPSAAERKH Non-modified HLA-DRB1*0701 Inquiry
TCR-L149 CMV TCRCD4-CMV#3 Human ~8kb Lentiviral VELRQYDPVAALFFFDIDLLLQR Non-modified HLA-DRB1*0701 Inquiry
TCR-L150 CMV TCRCD4-CMV#5 Human ~8kb Lentiviral VELRQYDPVAALFFFDIDLLLQR Non-modified HLA-DRB1*0701 Inquiry
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