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FOLH1

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This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-LX327 Anti-FOLH1 (X7X119) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X119 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX328 Anti-FOLH1 (X7X120) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X120 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX329 Anti-FOLH1 (X7X121) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X121 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX330 Anti-FOLH1 (X7X122) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X122 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX331 Anti-FOLH1 (X7X123) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X123 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX332 Anti-FOLH1 (X7X124) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X124 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX525 Anti-FOLH1 (X7X109) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X109 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX526 Anti-FOLH1 (X7X110) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X110 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX527 Anti-FOLH1 (X7X111) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X111 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX528 Anti-FOLH1 (X7X112) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X112 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX529 Anti-FOLH1 (X7X113) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X113 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX530 Anti-FOLH1 (X7X114) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X114 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX564 Anti-FOLH1 (X7X148) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X148 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX565 Anti-FOLH1 (X7X149) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X149 mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX566 Anti-FOLH1 (X7X150) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X150 mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX567 Anti-FOLH1 (X7X151) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X151 mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX685 Anti-FOLH1 (XG1-026) h(CD28-41BB-CD3ζ) CAR, pMMLV human XG1-026 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX686 Anti-FOLH1 (XG1-051) h(CD28-41BB-CD3ζ) CAR, pMMLV human XG1-051 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX687 Anti-FOLH1 (XG1-061) h(CD28-41BB-CD3ζ) CAR, pMMLV human XG1-061 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX688 Anti-FOLH1 (XG1-077) h(CD28-41BB-CD3ζ) CAR, pMMLV human XG1-077 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
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