HSP70

70 kD heat shock proteins(HSP70) are a family of conserved ubiquitously expressed heat shock proteins. Hsp70 proteins are central components of the cellular network of molecular chaperones and folding catalysts. They assist a wide range of folding processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and aggregated proteins, membrane translocation of organellar and secretory proteins, and control of the activity of regulatory proteins. Hsp70 is overexpressed in malignant melanoma and underexpressed in renal cell cancer.

Associated Disease
Anti-HSP70 CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC255 T cell Second cmHsp70.1 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC256 T cell Second Humanized cmHsp70.1 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
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