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IGF1R

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This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP7896 Anti-IGF1R (Ganitumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Ganitumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7897 Anti-IGF1R (Ganitumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Ganitumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7898 Anti-IGF1R (Dalotuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Dalotuzumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7899 Anti-IGF1R (Dalotuzumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Dalotuzumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7900 Anti-IGF1R (AVE1642) h(CD28-CD3ζ) CAR, pCDCAR1 Human AVE1642 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7901 Anti-IGF1R (AVE1642) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human AVE1642 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7902 Anti-IGF1R (M57) h(CD28-CD3ζ) CAR, pCDCAR1 Human M57 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7903 Anti-IGF1R (M57) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human M57 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7932 Anti-IGF1R (C8) h(CD28-CD3ζ) CAR, pCDCAR1 Human C8 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7933 Anti-IGF1R (C8) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C8 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7934 Anti-IGF1R (C4) h(CD28-CD3ζ) CAR, pCDCAR1 Human C4 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7935 Anti-IGF1R (C4) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C4 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7936 Anti-IGF1R (E2) h(CD28-CD3ζ) CAR, pCDCAR1 Human E2 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7937 Anti-IGF1R (E2) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human E2 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7938 Anti-IGF1R (B3) h(CD28-CD3ζ) CAR, pCDCAR1 Human B3 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7939 Anti-IGF1R (B3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human B3 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7940 Anti-IGF1R (D12) h(CD28-CD3ζ) CAR, pCDCAR1 Human D12 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7941 Anti-IGF1R (D12) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D12 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7942 Anti-IGF1R (M12-E01) h(CD28-CD3ζ) CAR, pCDCAR1 Human M12-E01 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7943 Anti-IGF1R (M12-E01) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human M12-E01 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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