MAGE-A3

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Associated Disease
Anti-MAGE-A3 TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-C119Z Human MAG-IC3 Human ~8kb Lentiviral EVDPIGHLY Non-modified HLA-A1 Inquiry
TCR-C120Z Human Mouse ~8kb Lentiviral KVAELVHFL Modified HLA-A*0201 Inquiry
TCR-C121Z Human Mouse ~8kb Lentiviral FLWGPRALV Non-modified HLA-A*0201 Inquiry
TCR-C122Z Human Mouse ~8kb Lentiviral KVAELVHFL Affinity enhanced HLA-A*0201 Inquiry
TCR-C123Z Human A10 Human ~8kb Lentiviral aa 168-176 Non-modified HLA-A*01 Inquiry
TCR-C124Z Human 13-18 Human ~8kb Lentiviral aa 168-176 Non-modified HLA-A*01 Inquiry
TCR-C125Z Human Human ~8kb Lentiviral EVDPIGHLY Affinity enhanced HLA-A*01 Inquiry
TCR-C126Z Human 6F9 Human ~8kb Lentiviral QHFVQENYLEY Non-modified HLA-DPB1*04:01 Inquiry
TCR-C127Z Human R12C9 Human ~8kb Lentiviral QHFVQENYLEY Non-modified HLA-DPB1*04:01 Inquiry
TCR-C128Z Human ESBI 648 Human ~8kb Lentiviral aa 167-176 Non-modified HLA-A1  Inquiry
TCR-C129Z Human TCRVα38/Vβ2 Human ~8kb Lentiviral KKLLTQHFVQENYLEY Codon optimized HLA-DP4 Inquiry
TCR-C130Z Human TCRVα3/Vβ28 Human ~8kb Lentiviral ALKVDVEERV Codon optimized HLA-A2 Inquiry
TCR-L059Z Human Murinized (from Human) 8kb Lentiviral KKLLTQHFVQENYLEY Murinized HLA-A2 Inquiry
TCR-L060 Human Murinized (from Human) 6700-8070bp retroviral vector KKLLTQHFVQENYLEY Murinized TCR HLA-A2 Inquiry
TCR-L245 Human Human ~8kb Lentiviral KVAELVHFL Non-modified HLA-A*0201 Inquiry
TCR-L246 Human Human ~8kb Lentiviral FLWGPRALV Non-modified HLA-A*0201 Inquiry
TCR-L359 Human EB81-103 Human ~8kb Lentiviral EVDPIGHLY Non-modified HLA-A1 Inquiry
TCR-L362 Human 6F9 Murinized ~8kb Lentiviral AA243-258 Murinized HLA-DP*0401 Inquiry
TCR-L363 Human R12C9 Murinized ~8kb Lentiviral AA243-258 Murinized HLA-DP*0401 Inquiry
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