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TLR4

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The protein encoded by this gene is a member of the Tolllike receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogenassociated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gramnegative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP9345 Anti-TLR4 (XHM509) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM509 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9346 Anti-TLR4 (XHM509) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM509 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9347 Anti-TLR4 (W7C11) h(CD28-CD3ζ) CAR, pCDCAR1 Human W7C11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9348 Anti-TLR4 (W7C11) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human W7C11 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9349 Anti-TLR4 (C2E3) h(CD28-CD3ζ) CAR, pCDCAR1 Human C2E3 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9350 Anti-TLR4 (C2E3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C2E3 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9351 Anti-TLR4 (HTA125) h(CD28-CD3ζ) CAR, pCDCAR1 Human HTA125 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9352 Anti-TLR4 (HTA125) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human HTA125 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9353 Anti-TLR4 (1203B) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1203B Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9354 Anti-TLR4 (1203B) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 1203B Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9355 Anti-TLR4 (NI-0101) h(CD28-CD3ζ) CAR, pCDCAR1 Human NI-0101 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9356 Anti-TLR4 (NI-0101) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human NI-0101 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9357 Anti-TLR4 (15C1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 15C1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9358 Anti-TLR4 (15C1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 15C1 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9359 Anti-TLR4 (3C3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3C3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9360 Anti-TLR4 (3C3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 3C3 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9361 Anti-TLR4 (HT52) h(CD28-CD3ζ) CAR, pCDCAR1 Human HT52 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9362 Anti-TLR4 (HT52) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human HT52 Rat scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9363 Anti-TLR4 (MTS510) h(CD28-CD3ζ) CAR, pCDCAR1 Human MTS510 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9364 Anti-TLR4 (MTS510) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human MTS510 Rat scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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