TRBC1

T-cell receptor beta constant 1 (TRBC1) is a protein that in humans is encoded by the TRBC1 gene. The α/β T-cell receptor (TCR) is a pan T-cell antigen, expressed on>90% of T-cell lymphomas and all normal T-cells. An overlooked feature of the TCR is that the β-constant region comprises 2 functionally identical genes: TRBC1 and TRBC2. Each T-cell expresses only one of these. Hence, normal T-cells will be a mixture of individual cells expressing either TRBC1 or 2, while a clonal T-cell cancer will express TRBC1 or 2 in its entirety.

Associated Disease
Anti-TRBC1 CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC094 T cell Second Jovi-1 ~8kb Retroviral scFv-(CD8stk)-CD28-CD3ζ Mouse Inquiry
CAR-LC095 T cell Second Jovi-1 ~8kb Retroviral scFv-(CH2CH3pvaa)-CD28-CD3ζ Mouse Inquiry
CAR-LC096 T cell Second Jovi-1 ~8kb Retroviral scFv-(IgG1)-CD28-CD3ζ Mouse Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON