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Overview
Ovarian germ cell tumor (OGCT) is an unusual type of ovarian cancer in which malignant (cancer) cells develop from the germ (egg) cells of the ovary. Ovarian germ cell tumors are more often in women who are 10 to 29 years old and generally affect just one ovary. Ovarian germ cell tumors are divided into the clinicopathological subtypes such as dysgerminoma (35-50% of OGCT), endodermal sinus tumor (20%), embryonal carcinoma (rare), polyembryoma (rare), choriocarcinoma (rare), teratoma and mixed GCT.
Sign and symptom
There are no obvious symptoms in the early stage. Nonetheless, tumors may be detected by regular gynecologic exams (checkups). Signs of ovarian germ cell tumor are swelling of the abdomen without weight gain in other parts of the body or bleeding from the vagina after menopause.
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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