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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Biomarkers that reveal the response to particular therapeutics are at the center of personalized medicine. Creative Biolabs has developed a cutting-edge Immune Monitoring Platform to assist in all aspects related to biomarker research: from Biomarker Discovery, to biomarker development and support of its clinical use. Flow cytometry is a powerful tool for biomarker discovery to assess immunotherapies by immune monitoring. We have built a team of scientists who have extensive experience in employing flow cytometry for biomarker discovery.
Given the importance of cell surface proteins as biomarkers of disease, efficient discovery tools are urgently needed. Flow cytometry is a powerful cellular analysis technique, which has proven to be valuable in research and clinical trial environment. Flow cytometry is a highly versatile method that is constantly expanding its field of application, including oncology, autoimmunity, tumor immunology, chemotherapy. Flow cytometry is highly useful not only in the discovery of new biomarkers but also in clinical validation and routine implementation. Flow cytometry simultaneously provides information about the phenotypic and functional characteristics of cells and enables quantification of large numbers of cells and assessment of their activation status, subset distribution, cytokine production profile, and other cellular functions. Furthermore, because flow cytometry allows the performance of many different types of assays, it yields a great deal of information, ranging from the elucidation of action mechanisms to functional assays. This technique plays an important role in the prioritization, verification, and clinical validation of new biomarkers.
As flow cytometry represents a robust and rapid platform for cell surface protein expression analysis, we have developed a powerful high throughput flow cytometry platform in 96- and 384-well assay format, allowing exploring cell type markers and activation markers in one assay at the single-cell level with high sensitivity and high flexibility. We provide direct expression and comparison analysis of biomarkers using multi-color fluorescence flow cytometry. Our scientists have accumulated extensive experience with various sample types including whole, frozen, and lysed blood, as well as peripheral blood mononuclear cells (PBMCs).
Biomarkers that we have analyzed include but are not limited to CD3, CD4, CD8, CD11, CD16, CD14, CD18 CD45, CD56, CD64, CD86, CD163, CD206, and CD209. We also have used the platform to identify many cell surface antigens that are influenced by common cell preparation methods such as enzyme digestion, cryopreservation, and fixation.
Flow cytometry is the premier technology to identify biomarkers to investigate functional responses to therapeutics at the single-cell level. Creative Biolabs accommodates everything from research assays for biomarker discovery to validated assays. For more information on flow cytometry for biomarker discovery, please feel free to contact us and further discuss with our scientists.
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