CD33

Myeloid cell surface antigen CD33, is a transmembrane receptor expressed on cells of myeloid lineage. It has numerous synonymous names including Siglec-3, sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67 or p67. CD33 is broadly expressed on acute myeloid leukemia (AML) blasts and, possibly some leukemic stem cells and has therefore been exploited as target for therapeutic antibodies. Some antibody-drug conjugates such as gemtuzumab ozogamicin target at CD33 for the treatment of patients with acute myeloid leukemia.

Anti-CD33 CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC155 T cell Second ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-LC194 T cell Second M195 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC195 T cell Second DRB2 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC196 T cell Second m2H12 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC197 T cell Second My9-6 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC280 T cell First Gemtuzumab ~8kb Lentiviral scFv-TetR/Tip-CD3ζ Human Inquiry
CAR-MZ004 T cell First ~8kb Retroviral scFv-DAP10 Human Inquiry
CAR-MZ158 T cell Second DRB2 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-1-M311-2 T cell First CAMPATH-1H 8kb Lentiviral scFv-CD28 Humanized Rat Inquiry
CAR-T-1-M311-G T cell First CAMPATH-1H 8kb Lentiviral scFv-FcεRIγ Humanized Rat Inquiry
CAR-T-1-M311-Z T cell First CAMPATH-1H 8kb Lentiviral scFv-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-2G T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD28-FcεRIγ Humanized Rat Inquiry
CAR-T-2-M311-2Z T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD28-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-4G T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD4-FcεRIγ Humanized Rat Inquiry
CAR-T-2-M311-4Z T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD4-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-8Z T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD8-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-BZ T cell Second CAMPATH-1H 8kb Lentiviral scFv-41BB-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-CZ T cell Second CAMPATH-1H 8kb Lentiviral scFv-b2c-CD3ζ Humanized Rat Inquiry
CAR-T-3-M311-2BZ T cell Third CAMPATH-1H 8kb Lentiviral scFv-CD28-41BB-CD3ζ Humanized Rat Inquiry
CAR-T-3-M311-2XZ T cell Third CAMPATH-1H 8kb Lentiviral scFv-CD28-OX40-CD3ζ Humanized Rat Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON