ErbB2

ErbB-2, also known as human epidermal growth factor receptor 2 (HER2), cluster of differentiation 340 (CD340), proto-oncogene Neu, is encoded by the ERBB2 gene. As a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family, ErbB2 has become an important biomarker and target of therapy for breast cancer. Not only the overexpression of ErbB2 occurs in breast cancer, but also it is strongly associated with the ovarian cancer, stomach cancer, lung adenocarcinoma, uterine cancer, salivary gland cancer, acute lymphoblastic leukemia (ALL), bladder cancer, childhood medulloblastoma, colorectal cancer, oral squamous cell carcinoma, germ-cell testicular tumor, cholangiocarcinoma, osteosarcoma, pancreatic adenocarcinoma and prostate cancer.

Associated Disease
Anti-ErbB2 CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-MZ019 T cell Second Trastuzumab ~8kb Lentiviral scFv-CD28-CD3ζ Humanized Inquiry
CAR-MZ029 T cell Second C6-B1D2 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ030 T cell Second C6MH3-B1 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ031 T cell Second C6ML3-9 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ032 T cell Second C6.5 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ033 T cell Second C6.5G98A ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ132 T cell Second L96 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ133 T cell Second N29 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ134 T cell Second 4D5 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ135 T cell Second L96 ~8kb Retroviral scFv-CD28-FcγR Mouse Inquiry
CAR-MZ136 T cell Second N29 ~8kb Retroviral scFv-CD28-FcγR Mouse Inquiry
CAR-MZ137 T cell Second 4D5 ~8kb Retroviral scFv-CD28-FcγR Mouse Inquiry
CAR-NK-1-M331-2 NK cell First FRP5 8kb Lentiviral scFv-CD28 Rabbit Inquiry
CAR-NK-1-M331-G NK cell First FRP5 8kb Lentiviral scFv-FcεRIγ Rabbit Inquiry
CAR-NK-1-M331-Z NK cell First FRP5 8kb Lentiviral scFv-CD3ζ Rabbit Inquiry
CAR-NK-2-M331-2Z NK cell Second FRP5 8kb Lentiviral scFv-CD28-CD3ζ Rabbit Inquiry
CAR-NK-2-M331-4G NK cell Second FRP5 8kb Lentiviral scFv-CD4-FcεRIγ Rabbit Inquiry
CAR-NK-2-M331-4Z NK cell Second FRP5 8kb Lentiviral scFv-CD4-CD3ζ Rabbit Inquiry
CAR-NK-2-M331-8Z NK cell Second FRP5 8kb Lentiviral scFv-CD8-CD3ζ Rabbit Inquiry
CAR-NK-2-M331-BG NK cell Second FRP5 8kb Lentiviral scFv-CD28-FcεRIγ Rabbit Inquiry
CAR-NK-2-M331-BZ NK cell Second FRP5 8kb Lentiviral scFv-41BB-CD3ζ Rabbit Inquiry
CAR-NK-2-M331-CZ NK cell Second FRP5 8kb Lentiviral scFv-b2c-CD3ζ Rabbit Inquiry
CAR-NK-3-M331-2BZ NK cell Third FRP5 8kb Lentiviral scFv-CD28-41BB-CD3ζ Rabbit Inquiry
CAR-NK-3-M331-2XZ NK cell Third FRP5 8kb Lentiviral scFv-CD28-OX40-CD3ζ Rabbit Inquiry
CAR-T-1-L337-2 T cell First OTI5C4 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-L337-G T cell First OTI5C4 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-L337-Z T cell First OTI5C4 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-1-M550-2 T cell First 8kb Lentiviral VHH-CD28 Camelid Inquiry
CAR-T-1-M550-G T cell First 8kb Lentiviral VHH-FcεRIγ Camelid Inquiry
CAR-T-1-M550-Z T cell First 8kb Lentiviral VHH-CD3ζ Camelid Inquiry
CAR-T-2-L337-2G T cell Second OTI5C4 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-L337-2Z T cell Second OTI5C4 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-L337-4G T cell Second OTI5C4 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-L337-4Z T cell Second OTI5C4 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-L337-8Z T cell Second OTI5C4 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-L337-BZ T cell Second OTI5C4 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-L337-CZ T cell Second OTI5C4 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-2-M550-2G T cell Second 8kb Lentiviral VHH-CD28-FcεRIγ Camelid Inquiry
CAR-T-2-M550-2Z T cell Second 8kb Lentiviral VHH-CD28-CD3ζ Camelid Inquiry
CAR-T-2-M550-4G T cell Second 8kb Lentiviral VHH-CD4-FcεRIγ Camelid Inquiry
CAR-T-2-M550-4Z T cell Second 8kb Lentiviral VHH-CD4-CD3ζ Camelid Inquiry
CAR-T-2-M550-8Z T cell Second 8kb Lentiviral VHH-CD8-CD3ζ Camelid Inquiry
CAR-T-2-M550-BZ T cell Second 8kb Lentiviral VHH-41BB-CD3ζ Camelid Inquiry
CAR-T-2-M550-CZ T cell Second 8kb Lentiviral VHH-b2c-CD3ζ Camelid Inquiry
CAR-T-3-L337-2BZ T cell Third OTI5C4 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-L337-2XZ T cell Third OTI5C4 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-T-3-M550-2BZ T cell Third 8kb Lentiviral VHH-CD28-41BB-CD3ζ Camelid Inquiry
CAR-T-3-M550-2XZ T cell Third 8kb Lentiviral VHH-CD28-OX40-CD3ζ Camelid Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

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