Fibroblast activation protein (FAP)

Fibroblast activation protein alpha (FAP) also called FAPA is a melanoma membrane-bound gelatinase, which encoded by the FAP gene in human. This protein a homodimeric integral membrane gelatinase belonging to the serine protease family. FAP is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds and malignant cells of bone and soft tissue sarcomas. Therefore, this protein is associated with epithelial cancers, breast cancer, colorectal cancer, skin cancer, pancreatic carcinomas, hepatocellular carcinomas, ovarian carcinomas and gastrointestinal carcinomas.

Associated Disease
Anti-Fibroblast activation protein (FAP) CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC223 T cell Second 73.3 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-LC224 T cell Second 73.3 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ141 T cell Second MO36 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ142 T cell Second MO36 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ143 T cell Third MO36 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ182 T cell Second mAb 73.3 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
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