NS3-4A protein

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. HCV has four structural proteins (C, E1, E2 and p7) and six nonstructural (NS) proteins (NS2, NS3, NS4A, NS4B, NS5A, and NS5B). NS5A is a hydrophilic phosphoprotein which plays an important role in viral replication, modulation of cell signaling pathways and the interferon response. It is known to bind to endoplasmic reticulum anchored human VAP proteins.

Associated Disease
  • HCV infection
Anti-NS3-4A protein TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-C184Z HCV DD31 Human ~8kb Lentiviral HSKKKCDEL Non-modified HLA-B*0801 Inquiry
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