Metagenomics Sequencing Service for Cancer-associated Virus
With years of experience in metagenomics sequencing for the identification of cancer-associated virus, Creative Biolabs has developed an efficient approach to improve the precision and recall rates of viral identification, which will accelerate the discovery rate of cancer-associated viruses.
Viral Metagenomics
Next-generation sequencing (NGS) technologies can be used to obtain a comprehensive and unbiased sequencing of the DNA present in a sample, without the need of any prior PCR or other amplification. The recent development of metagenomic sequencing makes it possible to sequence microbial genomes including viruses that may be present in a sample. Identifying viral sequences from metagenomic data is critical for downstream virus analysis. Viral metagenomics is nowadays routinely used for virus detection and discovery of novel viruses. More importantly, it is potential to extend our knowledge of the role of viruses in human diseases, such as cancer. Previous studies have shown that a considerable proportion of cancers are caused by infections, and also provided indications that additional cancer-associated virus may exist. With metagenomics sequencing, it is possible to perform a large-scale analysis of all virus infections that are present in cancers and in healthy individuals. Metagenomics sequencing of cancer specimens can be used in the discovery of a new cancer-associated virus.
Fig.1 Human papillomaviruses (HPVs) identified in skin and mucosal cancers. (Mollerup, 2019)
Metagenomics Sequencing Service for Cancer-associated Virus Creative Biolabs
Powered by our advanced SuPrecision™ Platform and experienced technical personnel, Creative Biolabs is fully competent and dedicated to providing metagenomics sequencing service for the discovery of cancer-associated virus. Our scientists have accumulated extensive experience in viral metagenomics sequencing and corresponding bioinformatics analysis. The bioinformatics analysis follows a number of distinct steps, including quality checking (check base calling accuracy), filtering (filtering out human and bacteria genomes), assembly, taxonomic classification, genotype abundances, community diversity and structure analysis.
Key Advantages
- Efficient and sensitive method for the identification of cancer-associated virus
- Sophisticated bioinformatics analysis
- Skilled in the discovery of unknown viruses or short viral sequences
- Highly professional Ph.D. level scientists
- Fast turnover time
Equipped with world-leading technology platforms and professional scientific staff, Creative Biolabs offers top-quality metagenomics sequencing service for the identification of cancer-associated virus. We are pleased to share our cutting-edge technology in the identification of viral sequences from metagenomic data. If you are interested in this service, please contact us for more information and a detailed quote.
Reference
- Mollerup, S.; et al. High-throughput sequencing-based investigation of viruses in human cancers by multienrichment approach. J Infect Dis. 2019, 220(8):1312-1324.
