HER2

Human epidermal growth factor receptor 2 (HER2), also known as ErbB-2, cluster of differentiation 340 (CD340), proto-oncogene Neu, is encoded by the ERBB2 gene. As a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family, HER2 has become an important biomarker and target of therapy for breast cancer. Not only the overexpression of HER2 occurs in breast cancer, but also it is strongly associated with the ovarian cancer, stomach cancer, lung adenocarcinoma, uterine cancer, salivary gland cancer, acute lymphoblastic leukemia (ALL), bladder cancer, childhood medulloblastoma, colorectal cancer, oral squamous cell carcinoma, germ-cell testicular tumor, cholangiocarcinoma, osteosarcoma, pancreatic adenocarcinoma and prostate cancer.

Associated Disease
Anti-HER2 CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC172 T cell Second 4D5 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC188 T cell Third Trastuzumab ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC252 T cell Third 6D ~8kb Nonviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC253 T cell Third 7G ~8kb Nonviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC366 T cell Third Trastuzumab ~8kb Lentiviral Human Inquiry
Anti-HER2 TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-C097Z Human HER2-1 Murinized ~8kb Lentiviral KIFGSLAFL Codon-optimized and murinized HLA-A2 Inquiry
TCR-C098Z Human HER2-2 Murinized ~8kb Lentiviral KIFGSLAFL Codon-optimized and murinized HLA-A2 Inquiry
TCR-C099Z Human HER2-3 Murinized ~8kb Lentiviral KIFGSLAFL Codon-optimized and murinized HLA-A2 Inquiry
TCR-C100Z Human HER2-4 Murinized ~8kb Lentiviral KIFGSLAFL Codon-optimized and murinized HLA-A2 Inquiry
TCR-C101Z Human Human ~8kb Lentiviral TYLPTNASL Non-modified HLA-A2 Inquiry
TCR-L049Z Human Human 8kb Lentiviral ErbB2 369–377 Non-modified HLA-A2 Inquiry
TCR-L050 Human Human 6700bp retroviral vector ErbB2 369–377 Non-modified TCR HLA-A2 Inquiry
TCR-L050Z Human Human 8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L051 Human Human 3817bp retroviral vector KIFGSLAFL Non-modified TCR HLA-A2 Inquiry
TCR-L221 Human A2 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L222 Human A3 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L223 Human B7 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L224 Human B10 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L225 Human D1 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L226 Human E1 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L227 Human E2 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L228 Human G3 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L229 Human G8 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L230 Human H3 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
TCR-L231 Human H5 Human ~8kb Lentiviral KIFGSLAFL Non-modified HLA-A2 Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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