Canine Anti-Canine TNF-α Monoclonal Antibody
Cat#:
AHQ-1025-Q2
Monoclonal antibody raised in canine against recombinant canine TNF-α. High specificity and affinity, validated for ELISA application.
Specifications
Background
Shipping and Storage
Clone ID
OC001
Antibody Type
Monoclonal Antibody
Host Species
Canine
Isotype
IgG1
Immunogen
Recombinant Canine TNF-α Protein
Specificity
Canine TNF-α
Species Reactivity
Canine
Conjugation
Unconjugated
Application
ELISA
Purity
≥95% (SDS-PAGE)
Purification Method
Protein A/G Purified
Buffer
0.01M PBS, pH 7.4
Formulation
Liquid
Target
Canine TNF-α
Synonyms
TNF; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2 (TNF-a)
Target Information
Tumor Necrosis Factor-alpha (TNF-α) is a key proinflammatory cytokine involved in immune regulation and host defense in dogs. It is primarily produced by activated macrophages, monocytes, and T lymphocytes in response to infection or tissue injury. TNF-α mediates inflammation by inducing the expression of adhesion molecules, chemokines, and other cytokines, playing a critical role in both acute and chronic inflammatory responses. In canine medicine, elevated TNF-α levels have been associated with various diseases, including autoimmune disorders, sepsis, cancer, and infectious diseases, making it an important biomarker and therapeutic target in veterinary immunology and inflammation research.
Gene ID
403922
Uniprot ID
P51742
Shipping and Storage
Shipped on ice. Store at 2-8 °C for short-term use. For long-term storage, keep at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles.