As a leader in the field of immunotherapy, Creative Biolabs has gained extensive experience developing mammalian and microbial production cell lines. The discovery experience companied with our advanced analytical capabilities enables us to identify and select clones that meet your product’s specific parameters and characteristics. After selecting the most appropriate clones, we optimize cell culture conditions to develop a high productivity cell line tailored to your specific product quality targets and desired productivity level, which is designed for robust, scalable manufacturing.
With powerful team of over 100 dedicated and skillful scientists and technicians, Creative Biolabs offers state-of-the-art cell culture development services to enable clone screening and selection, media optimization, seeding density, feeding and bioreactor process control relevant strategies. Our cell culture development platform is dedicated to maximizing the expression, enhancing process reproducibility and facilitating the future scale-up process. To ensure our cell culture development highly professional, we are equipped with a wide range of cell culture systems as well as advanced testing technologies including:
Our advanced platform enables us to perform more than 30 simultaneous development projects at different development stages. We offer maximum flexibility to ensure your project to be initiated at any stage of development. Here are some examples of our cell culture development support for your reference. Any other requirements, please feel free to let us know.
Standalone projects
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Late stage cell culture process development
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IND-enabling cell culture activities
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Perfusion and concentrated fed-batch platform
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We have developed a series of proprietary expression systems. These robust and scalable expression platforms have been used extensively to create many production cell lines. It accelerates development of cell lines for further production by using robust procedures and chemically defined media and feeds, to produce high levels of recombinant protein with a short timeline.
To optimize various product quality attributes, we have established a comprehensive series of approaches including, but not limited to.
Each step in the upstream process impacts the quality, purity, and quantity of the manufactured protein. At Creative Biolabs, we have developed various mammal -, bacteria and yeast-based cell culture developments in the last decade, giving us the insight necessary to identify and optimize upstream parameters that are critical for achieving a high-quality, cost-effective biomanufacturing process. Please contact us for more information and a detailed quote.
For Research Use Only | Not For Clinical Use