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Anti-Glycan Antibodies in Diagnostics

With years of experience and first-in-class technologies, Creative Biolabs has successfully developed universal antibody platforms and several efficient strategies to provide a series of anti-glycan antibodies products and services. We are very glad to provide a wide spectrum of services based on specific demands of customers with the highest quality and the most competitive price.

Anti-Glycan Antibodies Applied for Diagnostics

For every healthy individual, there are plenty of circulating antibodies in the blood and lymph, which are always ready to react with the stimulations of various antigens, especially for these nonself glycan structures on bacterial, fungal and parasite cells. These antibodies, including anti-glycan antibodies, play a very important role in the immune system and have been implicated in a number of diseases, such as autoimmune diseases, inflammatory, and cancers.

As with other antibodies, anti-glycan antibodies can be useful makers applied for laboratory and clinical diagnosis, including natural anti-glycan antibodies and prepared anti-glycan antibodies. Several anti-glycan antibodies have been reported to be associated with diseases. For examples, anti-chitobioside carbohydrate antibody, anti-laminaribioside carbohydrate antibodies, anti-Saccharomyces cerevisiae antibodies, and anti-mannobioside carbohydrate antibodies were proved to be novel serological markers in patients with inflammatory bowel disease, especially with Crohn’s disease. A newly investigated antibody anti-P1 antibody is another anti-glycan antibody that suggested to be a potential biomarker to diagnose cancers with higher specificity and sensitivity.

Plasma-derived anti-glycan antibodies of IgG and IgM isotype bind to polymeric presented Globo H glyco-clusters differentiating healthy controls from ovarian cancer comparable to CA125 (Pochechueva, 2017). Fig.1 Plasma-derived anti-glycan antibodies of IgG and IgM isotype bind to polymeric presented Globo H glyco-clusters differentiating healthy controls from ovarian cancer comparable to CA125 (Pochechueva, 2017).

What Creative Biolabs Can Do about Anti-Glycan Antibodies

Plenty of evidence has pointed out that anti-glycan antibodies are useful biomarkers in terms of diagnosis and prognosis of some diseases. As a world's leading biotechnology company, Creative Biolabs has successfully applied our manufactured antibodies to the diagnosis of relevant diseases. And based on these successful experience and powerful platforms, our scientific teams are pleased to offer a series of comprehensive one-stop services about anti-glycan antibodies to promote your research or projects. Our sphere of business includes but not limited to:

If you are interested or you have any questions, please directly contact us or send us an inquiry. Our customer service representatives are available 24 hours a day, 7 days a week.

Reference:

  1. Pochechueva, T.; et al. Naturally occurring anti-glycan antibodies binding to Globo H-expressing cells identify ovarian cancer patients. Journal of Ovarian Research. 2017, 10(1): 8.
For Research Use Only. Not For Clinical Use.
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