Dnl1; DNaseI; Deoxyribonuclease I

Enables deoxyribonuclease I activity. Involved in several processes, including DNA catabolic process; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Predicted to be located in extracellular region; nuclear envelope; and zymogen granule. Predicted to be active in nucleus. Is expressed in jejunum; metanephros; and tongue. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human DNASE1 (deoxyribonuclease 1).