TSC22 Domain Family Member 3; Glucocorticoid-Induced Leucine Zipper Protein; Delta Sleep-Inducing Peptide Immunoreactor; DSIP-Immunoreactive Peptide; TSC-22-Like Protein; TSC-22R; DSIPI; GILZ; Delta Sleep Inducing Peptide, Immunoreactor; DSIP-Immunoreactive Leucine Zipper Protein

This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants.