Fructose-Bisphosphatase 1; D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1; Fructose-1,6-Bisphosphatase 1; Liver FBPase; EC 3.1.3.11; FBPase 1; FBP; Growth-Inhibiting Protein 17; EC 3.1.3

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.