Full Name
Poly(ADP-Ribose) Polymerase Family Member 3

Keywords
Poly(ADP-Ribose) Polymerase Family Member 3; ADP-Ribosyltransferase (NAD+; Poly (ADP-Ribose) Polymerase)-Like 3; ADP-Ribosyltransferase Diphtheria Toxin-Like 3; NAD(+) ADP-Ribosyltransferase 3; Poly(ADP-Ribose) Synthetase-3; NAD+ ADP-Ribosyltransferase 3; Poly[ADP-Ribose] Synthase 3; PADPRT-3; ADPRTL3; ADPRT-3; ADPRT3

Background
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
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