SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 3; Sparc/Osteonectin, Cwcv And Kazal-Like Domains Proteoglycan (Testican) 3; TICN3; SPARC/Osteonectin, CWCV, And Kazal-Like Domains Proteoglycan 3; Testican-3; HSAJ1454; TES-3

This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.