Nei Like DNA Glycosylase 3; Zinc Finger, GRF-Type Containing 3; DNA Glycosylase/AP Lyase Neil3; Endonuclease VIII-Like 3; DNA Glycosylase FPG2; Nei-Like Protein 3; Nei Endonuclease VIII-Like 3 (E. Coli); Nei Endonuclease VIII-Like 3; DNA Glycosylase HFPG2; Endonuclease 8-Like 3

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]