Taxilin Gamma; Factor Inhibiting Activating Transcription Factor 4 (ATF4)-Mediated Transcription; Environmental Lipopolysaccharide-Responding Gene Protein; Lipopolysaccharide Specific Response-5 Protein; Lipopolysaccharide-Specific Response Protein 5; Factor Inhibiting ATF4-Mediated Transcription; CXorf15; ELRG

This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.