Zag; Alpha-2-Glycoprotein 1, Zinc

Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; detection of chemical stimulus involved in sensory perception of bitter taste; and positive regulation of T cell mediated cytotoxicity. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain; exocrine gland; genitourinary system; gut; and liver and biliary system. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human AZGP1 (alpha-2-glycoprotein 1, zinc-binding).