B4GALNT2

Full Name
Beta-1,4-N-Acetyl-Galactosaminyltransferase 2

Keywords
B4GALT; GALGT2; Beta-1,4-N-Acetyl-Galactosaminyltransferase 2 (Sid Blood Group)

Background
B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen (Montiel et al., 2003 [PubMed 12678917]).
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