Gba; Glucosylceramidase Beta 1

Enables glucosylceramidase activity. Involved in several processes, including establishment of skin barrier; response to dexamethasone; and response to testosterone. Predicted to be located in several cellular components, including endoplasmic reticulum; lysosome; and trans-Golgi network. Human ortholog(s) of this gene implicated in Gaucher's disease (multiple); Lewy body dementia; Parkinson's disease (multiple); and Parkinsonism. Orthologous to human GBA1 (glucosylceramidase beta 1).