Sialyl Lewis A

Full Name
Sialyl Lewis A

Keywords
Sialyl Lewis a; 3-Sialyl Lewis; Sialyl Lea tri

Background
Sialyl Lewis A is a carbohydrate epitope that is a key ligand for selectins, a family of cell adhesion proteins. Its structure is a tetrasaccharide containing sialic acid, fucose, galactose, and N-acetylglucosamine. This compound is involved in the rolling of white blood cells along the vascular wall during inflammation and is often overexpressed in various types of cancer, making it a potential diagnostic and therapeutic target.
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