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lumiliximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-FCER2/CD32 Therapeutic Antibody TAB-760 1mg Please Inquiry
Product Detail
Cat
TAB-760
Product Overview
Recombinant chimeric (primate/human) antibody expressed in CHO binding to human FCER2/CD32. Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Target
FCER2/CD32
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS
357613-86-6
Molecular Weight
47.75 kDa
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
At -20°C for one year.
Background
Introduction
Lumiliximab is a monoclonal antibody that targets CD23 and acts as an immunomodulator.
Antigen Description
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Function
IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding;
Gene ID
2208
Synonyms
FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF;
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