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Gomiliximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD23 Therapeutic Antibody TAB-231 1mg Please Inquiry
Product Detail
Cat
TAB-231
Product Overview
Recombinant monoclonal antibody to CD23. Gomiliximab is a monoclonal antibody acting as an immunosuppressive drug for the treatment of allergic asthma. It targets the low affinity IgE receptor (FcεRII or CD23). The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Target
CD23
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
CAS
357613-86-6
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti (human immunoglobulin E receptor type II) (human Macaca irus monoclonal IDEC 152 γ1 chain), disulfide with human Macaca irus monoclonal IDEC 152 kappachain, dimer
Molecular Weight
153860
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Size
1mg
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Function
IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding;
Gene ID
2208
Synonyms
FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF;
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