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gemtuzumab ozogamicin

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD33 Therapeutic Antibody TAB-H37 1mg Please Inquiry
Product Detail
Cat
TAB-H37
Product Overview
Recombinant Humanized (from mouse) antibody to Human CD33. Gemtuzumab ozogamicin is a drug-linked monoclonal antibody (an antibody-drug conjugate) that was used to treat acute myelogenous leukemia. Gemtuzumab is a monoclonal antibody to CD33 linked to a cytotoxic agent from the class of calicheamicins.
Type
IgG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, IHC and most other immunological methods.
CAS
220578-59-6
Purity
>95.0% as determined by analysis by SDS-PAGE.
Background
Antigen Description
CD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins.
Function
receptor activity; sugar binding;
Gene ID
945
Synonyms
CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3;
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