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pasotuxizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD3E Therapeutic Antibody TAB-H54 1mg Please Inquiry
Product Detail
Cat
TAB-H54
Product Overview
Recombinant Humanized antibody to Human CD3E
Type
(scFv - heavy - kappa) - (scFv - heavy - lambda)
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, WB and most other immunological methods.
CAS
1442657-12-6
Specificity
CD3E (CD3 epsilon) [Homo sapiens] ;
Protein Construction
Bispecific single chain antibodyscFv anti-FOLH1 (1-243) [humanized VH (Homo sapiens IGHV3- 11*01 (85.70%) – (IGHD )- IGHJ4*01) [8.8.14](1-121) – 15 – mer tris(tetraglycyl-seryl) linker (122-136) – humanized V-KAPPA (Homo sapiens IGKV1-16*01 (81.10%) – IGKJ2*01Q120>G (236)) [6.3.9](137-243)] -6-mer seryl-tetraglycyl-seryl linker (244-249) – scFv anti-CD3E (250-498) [Mus musculus VH (Mus musculus IGHV10-1*02 (91.90%) – (IGHD) – IGHJ3*01) [8.10.16] (250-374) -15-mertris(tetraglycyl-seryl) linker (375-389) – humanized V-LAMBDA (Homo sapiens IGLV7-43*01(85.10%)-IGLJ3*02 [9.3.9] (390-498)] – hexahistidine(499-504)
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Background
Antigen Description
CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11.
Function
SH3 domain binding; T cell receptor binding; protein heterodimerization activity; protein kinase binding; receptor activity; receptor signaling complex scaffold activity; receptor signaling protein activity; transmembrane signaling receptor activity;
Gene ID
916
Synonyms
CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell antigen receptor complex, epsilon subunit of T3; T3E; TCRE; FLJ18683;
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