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Zanolimumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD4 Therapeutic Antibody (HuMax-CD4) TAB-039 1mg Please Inquiry
Product Detail
Cat
TAB-039
Product Overview
Recombinant monoclonal antibody to CD4. Zanolimumab (expected trade name HuMax-CD4) is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
Target
CD4
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
CAS
652153-01-0
Trade name
humax-cd4
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin, anti-(human CD4 antigen) (human monoclonal 7G6 heavy chain), disulfide with human monoclonal 7G6 light chain, dimer.
Molecular Weight
147000
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Function
MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling re
Gene ID
920
Synonyms
CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
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