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Keliximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD4 Therapeutic Antibody TAB-171 1mg Please Inquiry
Product Detail
Cat
TAB-171
Product Overview
Recombinant monoclonal antibody to CD4. Keliximab is a monoclonal antibody for the treatment of severe chronic asthma. It suppresses the immune reaction by binding to white blood cells via the protein CD4. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Target
CD4
Type
IgG1 - lambda
Immunogen
Recombinant fragment (Human) corresponding to the external domain.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS
174722-30-6
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1,anti-(human CD4 (antigen)) (human-Macaca monoclonal CE9.1 g1-chain), disulfide withhuman-Macaca monoclonal CE9.1 l-chain, dimer
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Function
MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling re
Gene ID
920
Synonyms
CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
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