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Parsatuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human EGFL7 Therapeutic Antibody TAB-902 1mg Please Inquiry
Product Detail
Cat
TAB-902
Product Overview
Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFL7. Parsatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
Target
EGFL7
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, ELISA, IP, FC, FuncS, Neut, IF and most other immunological methods.
CAS
1312797-14-0
Predicted N terminal
EVQLVESG
Molecular Weight
147.8 kDa
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Introduction
Parsatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
Antigen Description
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.
Function
calcium ion binding;
Gene ID
51162
Synonyms
EGFL7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; ZNEU1; EGF-like protein 7; NOTCH4-like protein; vascular endothelial statin; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7; NEU1; VE-STATIN; RP11-251M1.2; MGC111117;
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