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Enlimomab pegol

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ICAM-1 Therapeutic Antibody Fab fragment TAB-241 1mg Please Inquiry
Product Detail
Cat
TAB-241
Product Overview
Recombinant monoclonal antibody Fab to ICAM-1.
Target
ICAM-1
Type
Fab' - G2a
Immunogen
Tissue / cell preparation (Human). (Burkitt"s lymphoma cell line RAJI).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
CAS
169802-84-0
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G 2a (human monoclonal BI-RR-1 anti-human antigen CD 54), disulfide with mouse monoclonal BI-RR-1 light chain, dimer, reaction product with alpha-(2-carboxyethyl)-ω-methoxypoly(oxy-1,2-ethanediyl)
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Function
cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;
Gene ID
3383
Synonyms
ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;
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